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Selected references 2010-2016 (PDFs are available on request):

Barkus E, Morrison PD, Vuletic D, Dickson J, Ell PJ, Pilowsky LS, Brenneisen R., Holt DW, Powell J, Kapur S, Murray RM. Does intravenous delta-9-tetrahydrocannabinol increase dopamine release? A SPET study. J Psychopharmacol 2010; 25: 1462-68.


Simoes-Wüst AP, Graos M, Duarte CB, Brenneisen R, Hamburger M, Mennet M, Ramos F MH, Schnelle M, Wächter R, Worel AM, von Mandach U. Juice of Bryophyllum pinnatum (Lam.) inhibits oxytocin-induced increase of the intracellular clacium concentration in human myometrial cells. Phytomedicine 2010; 17: 980-86.


Brenneisen R, Meyer P, Chtioui H, Saugy M, Kamber M. Plasma and urine profiles of delta-9-tetrahydrocannabinol (THC) and its metabolites 11-hydroxy-THC and 11-nor-9-carboxy-THC after cannabis smoking by healthy volunteers to estimate recent consumption of athletes. Anal. Bioanal. Chem. 2010; 396: 2493-2502.


Berset J-D, Brenneisen R, Mathieu C. Analysis of llicit and illicit drugs in waste, surface and lake water samples using large volume direct injection high performance liquid chromatography – Electrospray tandem mass spectrometry (HPLC-MS/MS). Chemosphere 2010; 81: 859-66.

Brenneisen R, Briellmann T, Rentsch K, Deom A, Küffer H, Scholer A,  Binz P-A. Swiss Guidelines 2011 for Drugs of Abuse Testing. Toxichem  Krimtech 2011;78:391

Mathieu C, Rieckermann J, Berset J-D, Schürch S, Brenneisen R. Assessment of total uncertainty in cocaine and benzoylecgonine wastewater load measurements. Water Research 2011; 45: 6650-60.


Hysek CM, Simmler LD, Ineichen M, Grouzmann E, Hoener MC, Brenneisen R, Huwyler J, Liechti ME. The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA (“Ecstasy”) in humans. Clin Pharm Ther (advance online pub, doi 10.1038/clpt.2011.78)


Morrison PD, Nottage J, Stone JW, Bhattacharyya S, Tunstall N, Brenneisen R, Holt D, Wilson D, Sumich A, McGuire P, Murray RM, Kapur S, Ffytche D. Disruption of frontal theta coherence by Δ9-tetrahydrocannabinol is associated with positive psychotic symptoms. Neuropsychopharmacology 2011; 36: 827-36.


Wächter R, Brenneisen R, Hamburger M, Mennet M, Schnelle M, Worel AM, Simões-Wüst AP, von Mandach U. Leaf press juice from Bryophyllum pinnatum (Kalanchoe pinnata L.) induces myometrial relaxation. Phytomedicine 2011; 19: 74-82 .


Patsenker E, Stoll M, Millonig G, Agaimy A, Wissniowski T, Schneider V, Mueller S, Brenneisen R, Seitz H, Ocker M, Stickel F. Cannabinoid receptor type I modulates alcohol-induced liver fibrosis. Molecular Medicine 2011; 17: 1285-94.

Stone JM, Morrison PD, Brugger S, Nottage J, Bhattacharyya S, Sumich A, Wilson D, Tunstall N, Feilding A, Brenneisen R, McGuire P, Murray RM, Ffytche DH. Communication breakdown: delta-9-tetrahydrocannabinol effects on pre-speech neural coherence. Molecular Psychiatry 2012; 17: 268-69.

Schuler V, Suter K, Fürer K, Eberli D, Horst M, Betschart C, Brenneisen R, Hamburger M, Mennet M, Schnelle M, Simões-Wüst AP, von Mandach U. Bryophyllum pinnatum inhibits detrusor contractility in porcine bladder strips - A pharmacological study towards a new treatment option of overactive bladder. Phytomedicine 2012; 19: 947-51.

Joerger M, Wilkins J, Fagagnini S, Baldinger R, Brenneisen R, Schneider  U, Goldman B, Weber M. Single-dose pharmacokinetics and tolerability of  oral delta-9-tetrahydrocannabinol in patients with amyotrophic lateral  sclerosis. Drug Metabolism Letters 2012; 6: 102-108.

Englund A, Morrison PD, Nottag J, Hague D, Kane F, Bonaccorso S, Stone JM, Reichenberg A, Brenneisen R, Holt D, Feilding A, Walker L, Murray RM, Kapur S. Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment. J Psychopharmacol 2013; 27: 19-27.                  


Walter M, Gerber H, Kuhl HC, Schmid O, Joechle W, Lanz C, Brenneisen R, Schächinger H, Riecher-Rössler A, Wiesbeck GA, Borgwardt SJ. Acute effects of intravenous heroin on the hypothalamic-pituitary-adrenal axis response: A controlled trial. J Clin Psychopharmacol 2013; 33: 193-98.

Fürer K, Raith M, Brenneisen R, Mennet M, Simões-Wüst AP, von  Mandach U, Hamburger M, Potterat P. Two new flavonol glycosides and a  metabolite profile of Bryophyllum pinnatum, a phytotherapeutic used in  obstetrics and gynaecology. Planta Med 2013; 79: 1565-71.

Gasser P, Holstein P,  Michel Y, Doblin R, Yazar-Klosinski B, Passie T,  Brenneisen R. Safety and efficacy of LSD-assisted psychotherapy in  participants with anxiety associated with life-threatening diseases: A  randomized active placebo-controlled phase 2 pilot study, J Nervous  Mental Dis,
epub ahead 2014/03/0.

Walter M, Denier N, Gerber H, Schmid O, Lanz C, Brenneisen R, Riecher- Rössler A, Wiesbeck G, Scheffler K, Seifritz E, McGuire P, Fusar-P Paolo,  Borgwardt S. Orbitofrontal response to drug-related stimuli after heroin  administration. Addiction Biol 2014 (doi:10.1111/adb.12145).


Freeman D, Dunn G, Murray RM, Evans N, Lister R, AntleyA, Slater M,  Godlewska B, Cornish R, Williams J, Di Simplicio M, Igoumenou A,  Brenneisen R, Tunbridge EM, Harrison P, Harmer CJ, Cowen P,  Morrison PD. How cannabis causes paranoia: using the intravenous  administration of ∆9-tetrahydrocannabinol (THC) to identify the key  cognitive mechanisms leading to paranoia. Schizophrenia Bull
2014, epub ahead July 15.

Ngamgwe RF, Yankam R, Chouna JR, Lanz C, Furrer J, Schürch S, Kaiser M, Lenta BN, Ngouel S, Etienne Tsamo E, Brenneisen R.
Procerenone: a fatty acid triterpenoid from the fruit pericarp of Omphalocarpum procerum (Sapotaceae). Iranian J Pharm Res 2014 ; 13: 1425-1430.

Schmid Y, Enzler F, Gasser P, Grouzmann E, Preller KH, Vollenweider FX, Brenneisen R, Müller F, Borgwardt S, Liechti M. Acute effects of LSD in healthy subjects. Biol Psych, e-pub 2015/01/13.


Schmidt A, Walter M, Gerber H, Seifritz E, Brenneisen R, Wiesbeck GA, Riecher-Rössler A, Lang UE, Borgwardt S. Normalising effect of heroin maintenance treatment on stress-induced brain connectivity. Brain 2015; 138: 217-28.

Patsenker E, Sachse P, Chicca A, María Salomé Gachet  MS, Schneider V, Mattsson J, Lanz C, Worni M, de Gottardi A, Semmo M, Hampe J, Schafmayer J,
Brenneisen R, Gertsch J, Stickel F,Semmo N. Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation. Int J Mol Sci 2015; 16: 7057-7076; doi:10.3390/ijms16047057.

Fürer K, Eberli D, Betschart C, Brenneisen R, De Mieri M, Hamburger M, Mennet-von Eiff M, Potterat O, Schnelle M, Simões-Wüst AP, von Mandach U. Inhibition of porcine detrusor contractility by the flavonoid  fraction of Bryophyllum pinnatum – a potential phytotherapeutic drug for the treatment of the overactive bladder syndrome. Phytomed. 2015; 22: 158-64.

Oufir M, Seiler C, Gerodetti M, Gerber J, Fürer K, Mennet-von Eiff M, Elsas S-M, Brenneisen R, von Mandach U, Hamburger M, Potterat O.
Quantification of bufadienolides in Bryophyllum pinnatum leaves and manufactured products by UHPLC-ESIMS/MS. Planta Med 2015; 81: 12-13.

Lanz C
, Mattsson J, Soydaner U, Brenneisen R. Medicinal cannabis: In vitro validation of vaporizers for the smoke-free inhalation of cannabis. Plos one 2016, Jan. 19 (open access).






 
 
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